Few studies have explored the impairment of the immune response in DS through the analysis of serum inflammatory mediators [7], particularly in children [11], where significant changes in the levels of Interleukin-4 (IL-4), Interleukin-10 (IL-10), Interferon gamma (IFN-gamma), and tumor necrosis factor alpha (TNF-alpha) were noted. Here, IL4 is linked to Dravet syndrome.