To address if experimental GALT mRNA therapy improves motor-related phenotypes in a mouse model of classic galactosemia (question 1), we compared the rotarod and composite phenotype scoring results from assessment 1 between the WT, treated, and untreated GalT-KO animals in cohort 1 (n = 8; 4 males and 4 females). This evidence concerns the gene GALT and classic galactosemia.