The recombinant CCDC7241aa protein, derived from the chimeric circular RNA CCDC719–13, promotes TRIM21-mediated SLC7A11 ubiquitination and demonstrates synergistic effects with both docetaxel and enzalutamide across AR-negative (PC3) and AR-positive (LNCaP, VCaP, 22RV1) PCa cell lines [32]. The gene discussed is SLC7A11; the disease is posterior cortical atrophy.