There was a 13.8% increase in immunosuppressive FoxP3+ CD4+ T cells as a total percentage of T cells (Figure 4D) in KEAP1 KO versus WT tumors; however, we did not detect a difference in the activation state of anti-tumor CD8+ T cells (Figure 4E) or NK cells (Figure 4F). Here, KEAP1 is linked to neoplasm.