The pooled RRs of all-grades ALT, AST and TB elevation were 0.36 (95% CI 0.24–0.52, P < 0.001), 0.44 (95% CI 0.36–0.54, P < 0.001) and 0.83 (95% CI 0.50–1.39, P = 0.48), respectively. This evidence concerns the gene GPT and tuberculosis.