NSUN2 and acute myeloid leukemia: NSUN2 is significantly overexpressed in AML patients, mechanistically, NSUN2 mediates m5 C methylation in the 3’UTR of FSP1 mRNA, enabling YBX1 binding to stabilize the transcript and maintain FSP1 protein levels and protecting AML cells from ferroptotic stress by suppressing lipid peroxidation [87].