High-dimensional flow cytometry of tumor-infiltrating T cells (TILs) revealed four clusters enriched for tumor-specific OT-I T cells expressing CD69 and PD-1, and differing in markers such as CD39, CD103, TCF1, TOX and TIM3 (Fig. 5a–f and Extended Data Fig. 7a). The gene discussed is TOX; the disease is neoplasm.