In AF, enrichment for prioritized genes including SRC, GATA1 and HSPA8 was identified in 658 pathways, of which 14 were relevant pathways associated with AF, including processes regulating cardiac conduction, response to hypoxia and regulation of immune system process (Supplementary Fig. 3 and Supplementary Information). The gene discussed is GATA1; the disease is atrial fibrillation.