Immunohistochemistry (IHC) of tumor samples and normal tissues from the Human Protein Atlas (HPA) database revealed that CLDN12 protein was highly expressed in LUSC, PRAD, COAD, READ, LIHC, cholangiocarcinoma (CHOL), breast invasive carcinoma (BRCA), and BLCA tumor tissues (Figure S5). The gene discussed is CLDN12; the disease is neoplasm.