PEBP1 and rheumatoid arthritis: Given these functions, RKIP has garnered attention for its involvement in a range of inflammatory and immune-related conditions, including multiple sclerosis, Alzheimer’s disease, rheumatoid arthritis, diabetic nephropathy, systemic inflammatory response syndrome, asthma, allergy, inflammatory bowel disease, colitis, Sjogren’s syndrome, and certain infections such as Helicobacter pylori and viral infections (30, 41, 45, 46, 55, 56, 83–87).