A key component of P. grandiflorus, platycodin D, and the active ingredients in P. ginseng, ginsenoside Rh1 have been reported to significantly reduce the expression of Bax, cleaved-caspase-3, and cleaved-caspase-9, while increasing the expression of Bcl-2 and Bcl-XL in the kidneys of STZ-induced DKD mice. The gene discussed is BCL2L1; the disease is diabetic kidney disease.