While NETs typically consist of common components such as DNA, histones, MPO, and NE, systematic studies focusing on the specific protein profiles and post-translational modifications (such as citrullination) of NETs in the circulatory systems of patients with BD, particularly those utilizing high-throughput techniques like mass spectrometry or quantitative proteomics, have yet to be comprehensively reported. This evidence concerns the gene MPO and Behcet disease.