Significant differences were observed in all five biomarkers (P < 0.05).The median ESR in the PJI group was 53.00 mm/h (IQR: 41.00–76.00), significantly higher than that in the AF group (24.00 mm/h, IQR: 15.00–44.50).Median CRP levels were 16.20 mg/L (IQR: 8.58–30.20) in the PJI group, compared to 6.95 mg/L (IQR: 3.22–12.94) in the AF group. This evidence concerns the gene CRP and juvenile polyposis syndrome.