METTL16 and lung carcinoma: In gastric cancer, METTL3 interacts with poly(A) binding protein cytoplasmic 1 (PABPC1) and stabilizes its association with the cap-binding complex eukaryotic translation initiation factor 4F (eIF4F), whereas METTL16 directly interacts with the translation repressor eIF4E2 in lung cancer.32