SCN5A and Schnyder corneal dystrophy: The Shanghai Score was established in 2017 to address concerns about overdiagnosis, particularly due to false-positive SCB testing in healthy individuals (11, 12) This point-based system incorporates a positive history of 1) suspected arrhythmogenic syncope, 2) early onset of atrial fibrillation/flutter, 3) nocturnal agonal respiration, 4) documented VF/polymorphic ventricular tachycardia (VT), 5) positive genotype (SCN5A), 6) definite BrS in first- or second-degree family members and 7) family history of sudden cardiac death (SCD).