For example, IL‐18 enhances tumor‐infiltrating lymphocyte activation and promotes antitumor responses [40], IL‐1α exerts dual roles by driving cachexia [41] and priming antitumor immunity [42, 43], IL‐4 promotes epithelial tumor growth and immune evasion [44–46]; and both IL‐33 and IL‐7 exhibit pleiotropic effects on tumor immunity [47–50]. This evidence concerns the gene IL4 and neoplasm.