Disease activity was assessed using the Disease Activity Score in 28 Joints using C-reactive Protein (DAS28-CRP), the Clinical Disease Activity Index (CDAI), the Simplified Disease Activity Index (SDAI), and the Health Assessment Questionnaire (HAQ) for RA, and the Ankylosing Spondylitis Disease Activity Score using C-reactive Protein (ASDAS-CRP), the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), and the Bath Ankylosing Spondylitis Functional Index (BASFI) for SpA. The gene discussed is CRP; the disease is spondylitis.