showed that the RNA methyltransferase METTL3 is upregulated in tumour tissue, and that METTL3 overexpression promotes proliferation, migration, invasion, glucose uptake and lactate production by enhancing m6A modification and expression of AKR1B10; METTL3 knockdown had the opposite effects and suppressed tumour growth in vivo. This evidence concerns the gene AKR1B10 and neoplasm.