There are several factors that increase the risk of infection in MM, including the presence of hypogammaglobulinemia; advancing age; comorbidities (e.g., heart and lung disease, kidney failure); steroid‐induced immunosuppression; mucositis and bone marrow failure caused by cytotoxic treatment; and the cumulative effects of the principal disease and treatment that can decrease antibody response to infections and vaccines and lead to T‐cell, dendritic cell, and natural killer cell dysfunction (related to anti‐CD38 antibody treatment) [3, 4, 12]. Here, CD38 is linked to infection.