Outcomes including serum interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) levels, synovial fluid matrix metalloproteinase-3 (MMP-3) and tissue inhibitor of metalloproteinases-1 (TIMP-1) levels, visual analog scale (VAS) score, Western Ontario and McMaster Universities Arthritis Index (WOMAC) score, Lysholm score and complications were all recorded and compared. This evidence concerns the gene IL6 and arthritic joint disease.