It has been reported that within 1 year after stroke onset, inflammatory markers such as interleukin-6 (IL-6), interleukin-10 (IL-10), and tumor necrosis factor-alpha (TNF-α) are significantly elevated, with notable increases in the IL-6/IL-10 and TNF-α/IL-10 ratios (11). The gene discussed is TNF; the disease is Stroke.