Other Genetic Forms of HIES/Combined Immunodeficiency (CID): Although conditions like DOCK8 deficiency (now classified as CID) can present with high IgE and eczema, our patient's history was dominated by bacterial and fungal infections without severe viral infections, aligning more with STAT3-HIES. This evidence concerns the gene DOCK8 and hyperinsulinemic hypoglycemia, familial, 4.