Participants in the highest irisin tertile had a higher BMI (p = 0.018), WC (p = 0.007), body fat mass (p = 0.004), HOMA‐IR (p < 0.001) and a higher prevalence of abdominal obesity (p = 0.009) and sarcopenic obesity (p = 0.046) compared to the lowest tertile. This evidence concerns the gene FNDC5 and Abdominal obesity.