Closer examination revealed that 35 of the genes that showed sex‐specific associations with AD endophenotypes are known to be subject to XCI (Table S4), while three are known XCI escapees (STS, SYAP1, and TXLNG), four are classified as variable escape genes (TSIX, TRPC5, DGAT2L6, and FOXO4), and one is in the pseudoautosomal region (ASMTL‐AS1) and is expected to escape XCI.57 This evidence concerns the gene ASMTL and Alzheimer disease.