ADIPOR1 and obesity due to melanocortin 4 receptor deficiency: Since our research group demonstrated by immunohistochemistry, that women with overweight or obesity had a lower expression of this adipokine and higher ADIPOR1 expression in breast cancer tissue [18], and that adiponectin plays a role in the TME of breast cancer; the objective of this study is to analyze the ADIPOQ and ADIPOR1 levels in fresh breast tumour tissue and adjacent adipose tissue of postmenopausal women with this cancer.