ADIPOR1 and obesity due to melanocortin 4 receptor deficiency: On the other hand, we observed significantly higher ADIPOR1 levels only in breast adipose tissue adjacent to the tumour in postmenopausal women with obesity and tumour size > 2.0 cm and clinical stage II/III (p = 0.019 and p = 0.025, respectively, Fig. 2, Panel b) compared with postmenopausal women with a normal BMI.