Elevated plasma glucose also correlated significantly with markers of insulin resistance and metabolic syndrome risk, including HOMA-IR (r = 0.39, p = 0.01), triglyceride/HDL cholesterol ratio (r = 0.33, p = 0.04) and leptin/adiponectin ratio (r = 0.37, p = 0.02). The gene discussed is LEP; the disease is metabolic syndrome.