In the tumour centre, tumours in the stroma-high TSR group, the immature DR group, and the high SMAPS group were associated with lower densities of CD3+ T cells (p < 0.0001 for all), M1-like macrophages (p < 0.0002 for all), and CD66B+ granulocytes (p < 0.0001 for all). The gene discussed is CEACAM8; the disease is neoplasm.