This study investigates the prognostic impact of albumin, the urea‐to‐albumin ratio (UAR), and albumin‐to‐creatinine ratio (ACR) in patients with heart failure with mildly reduced ejection fraction (HFmrEF), since hypoalbuminemia, renal disease and malnutrition often coincide with heart failure (HF). This evidence concerns the gene ALB and nutritional deficiency disease.