APOE and Alzheimer disease: Figures 4 and 5 demonstrates that Pa-MACRO successfully identified several AD-related proteomic markers (ApoE, ApoB, CRP, MIG, and CgA) (Serrano-Pozo et al. 2021), imaging phenotypes including the right and left hippocampus, parahippocampus, and temporal pole regions (Frisoni et al. 2008, Fan et al. 2019, Geigenmüller et al. 2024).