ABCG2 and hyperuricemia: We have also reported [6] that two common dysfunctional variants of ABCG2, non-functional p.Q126X (rs72552713) and half-functional p.Q141K (rs2231142), create a greater population risk for progression of hyperuricemia than typical environmental risk factors by using population-attributable fraction (PAF, also known as population-attributable risk percent: PAR%).