TNF and Allergy: Consequently, it limits pro-inflammatory cytokines, such as interferon (IFN)-γ, tumor necrosis factor (TNF), and interleukin (IL)−17 [9, 10], while enhancing levels of immunosuppressive cytokines like IL-10 [11], which offers protection from inflammation but raising susceptibility to intramacrophagic infections and allergy in early life [12].