The hypothalamic neurons from male pups from mothers fed HFD showed reduced response to hyperglycemia stimuli in vitro, even for the neuropeptide Y (NPY) neurons and for the pro‐opiomelanocortin (POMC) neurons, suggesting offspring hypothalamic glucose uptake was reduced by maternal HFD consumption, which can lead to hyperphagia and food imbalance (Chen et al. 2014). Here, NPY is linked to Hyperglycemia.