In the placentas from women with obesity, was observed a decrease in the activity of the antioxidant enzymes superoxide dismutase (SOD) and catalase, accompanied by increased levels in the nitrotyrosine residues, suggesting that the placenta antioxidant response of women with obesity is affected (Santos‐Rosendo et al. 2020). This evidence concerns the gene CAT and obesity due to melanocortin 4 receptor deficiency.