In fact, significant negative correlations in AD were observed with 5HT2a (r = −0.36, p = 0.001), 5HT4 (r = −0.28, p = 0.017), GABAa (r = −0.30, p = 0.006), and mGluR5 (r = −0.26, p = 0.011), indicating that regions where MIND decreased compared to what was expected from age‐ and sex‐matched healthy population references were partly spatially co‐localized with areas of higher normative serotonergic, GABAergic, and glutamatergic density. This evidence concerns the gene HTR4 and Alzheimer disease.