Figure 5E clearly showed that CD133- CRC cells exhibited a markedly higher viability compared to CD133+ CRC cells after treatment with the same concentration of SLNT. It is worth mentioning that CD133+ CRC cells were considered to exhibit stemness characteristics. Therefore, the results in Figure 5E also reflected the strong stemness-inhibitory effect of SLNT on CRC cells. This evidence concerns the gene PROM1 and colorectal carcinoma.