Zhongfeng Xingnao Decoction was shown to reduce inflammatory responses and the volume of perihematomal edema by regulating the activation of NLRP3 inflammasome after intracerebral hemorrhage, which is related to the CaMKII/NF-κB p65/NLRP3/GSDMD signaling axis (Yu et al., 2025). This evidence concerns the gene NFKB1 and intracerebral hemorrhage.