Regulating NMDA receptors in the periaqueductal grayInhibiting NLRP3 inflammasomeImproving the function of vascular endotheliumMyocardial SOD↑, oxygen free radicals↓, and improve the lipid metabolism disorder in diabetic miceRegulating the AMPK-ULK1 signaling pathway. The gene discussed is ULK1; the disease is Disorder of lipid metabolism.