Downstream of ANT4.1 (5.3 Mbp) identified in the current study is the multi-allelic Co-3 locus (3.36 Mbp) and Phg-3 gene for ALS while upstream at 9.08 Mbp is the Andean Co-15 locus (Sousa et al., 2015), which suggests that this QTL is different from these Co genes and Phg-3 for ALS. Here, MT-CO3 is linked to amyotrophic lateral sclerosis.