CXCR4 and Decreased total neutrophil count: While CXCR4 antagonism corrected peripheral blood neutropenia in CXCR2 LOF mice (Figures 1B-E), it did not appear to affect the count of red blood cells or platelets in both CXCR2 LOF and control mice (Supplementary Figures 1A, B), consistent with a previous report (38).