Given the bilateral hilar lymphadenopathy and hypercalcemia, serum angiotensin-converting enzyme (ACE) was also within the normal range (35.5 U/L; NR, 22–62 U/L), and both the tuberculosis interferon-γ release assay (TB-IGRA) and sputum cultures for Mycobacterium tuberculosis were negative. The gene discussed is ACE; the disease is hypercalcemia disease.