The final assignment of different NK cell clusters, elaborated in detail in the section below, is indicated on the left of the heatmap in Figure 3F and are annotated as peripheral early NK cells (early pNK), peripheral mature NK cells (mature pNK), peripheral adaptive NK cells (adaptive pNK either CD49a+ or CD49a- ), liver tr-NK, adaptive/memory liver resident NK cells (ml-NK), liver circulating NK (cNK), liver circulating adaptive NK (adaptive cNK), tr-NK precursor (pre tr-NK), liver circulating NK cells or adaptive cNK prevalent in HCC (HCC cNK, adaptive HCC cNK) and Lt-ILC1s. This evidence concerns the gene ITGA1 and hepatocellular carcinoma.