Clinically, several scenarios exist: (1) APS-like obstetric features with two positive aPL tests but <12-week interval; (2) Obstetric APS features with persistent low-titer aPL positivity; (3) Obstetric APS features with negative classic aPLs; (4) Laboratory APS criteria met but with atypical obstetric manifestations (e.g., recurrent miscarriages, unexplained late fetal loss, or severe preeclampsia with placental abruption). Here, FASLG is linked to autoimmune polyendocrinopathy.