This case involves a patient with no clear history of autoimmune diseases but multiple immunological abnormalities, including ANA (speckled pattern 1:1000), positive anti-SSA and anti-SSB antibodies, transient low-titer ACL-IgM, and a one-time high-titer anti-β2-GP1 positivity. The gene discussed is CD40LG; the disease is autoimmune disease.