AML (from MDS): ASXL1 p.E635fs15, CSF3R p.T618I, CREBBP p.Y1733fs, NRAS p.G12D, NRAS p.G12V, NRAS p.G12S, RUNX1 p.F1165, FLT3-ITD. The gene discussed is RUNX1; the disease is myelodysplastic syndrome.