BNIP3 and chronic kidney disease: Oroxylin A (OA), an active ingredient extracted from Scutellaria baicalensis, was shown to maintain mitochondrial homeostasis, alleviate kidney injury and delay the progression of AKI to CKD in IRI and cisplatin AKI models by inducing PPARα-BNIP3 signaling pathway (Yao et al., 2022).