TLR2 and colorectal carcinoma: Guo et al. (2013) examined tissues from patients with CRC and observed an increase in the levels of TLR2 in these samples. They also declared that by targeting TLR2, the invasion and migration of CRC cells are substantially reduced (Guo et al., 2013). It was discovered that the invasion and migration of CRC cells through TLR2 is reduced by miR-143. Based on a xenograft mouse model, it was observed that the inhibition of CRC cell colonization in vivo is achieved through the re-expression of miR-143 (Guo et al., 2013).