Contrastingly, accumulating evidence identifies ZFAS1 as a context-dependent oncogene, showing marked overexpression in HCC, gastric cancer, and colorectal cancer where it drives tumor progression via regulation of proliferation, angiogenesis, and metastatic dissemination [[33], [34], [35], [36], [37], [38]]. This evidence concerns the gene ZFAS1 and neoplasm.