Several in vivo animal models are currently being discussed to target different research aims (Kazemi et al., 2023), among others, Brown Norway rat and BALB/c mice strains models are the most commonly used ones for food allergy because of high IgE responses (Ballegaard et al., 2023; Ballegaard et al., 2019; Dai et al., 2023). Here, IGHE is linked to food allergy.