HSD3B2 and congenital adrenal hyperplasia: Congenital adrenal hyperplasia (CAH) refers to a group of seven monogenic adrenal disorders, caused by pathological variants in genes coding for enzymes in the adrenal steroidogenic pathway: CYP21A2, CYP11B1, CYP17A1, HSD3B2, STAR, CYP11A1, and POR (9).