NFKB1 and Alzheimer disease: KEGG enrichment pathways included calcium signaling pathway, TNF, PI3K-Akt, HIF-1, neuroactive ligand-receptor interaction, cAMP, MAPK, apoptosis, and NF-κB signaling pathways, among which the calcium signaling pathway is closely related to AD mechanisms and may be an essential signaling pathway through which MFXD improves cognitive dysfunction.