In the study conducted in China by Lv et al. regarding the feasibility and effectiveness of hysteroscopic suture fixation of LNG-IUS for adenomyosis, the VAS, PBAC score, and cancer antigen 125 (CA-125) were significantly reduced (p < 0.001), with a conclusion of having a low expulsion rate with significant improvement in dysmenorrhea and bleeding [39]. The gene discussed is MUC16; the disease is adenomyosis.