Objective: The objective of this study is to evaluate the prevalence and interplay of traditional and non-traditional CV risk factors in CKD, with a focus on biomarkers (IL-6, asymmetric dimethylarginine (ADMA), homocysteine, uric acid) and echocardiographic findings, and to determine their ability to predict N-terminal pro-brain natriuretic peptide (NT-proBNP) levels. This evidence concerns the gene IL6 and chronic kidney disease.